SCIENCE
Bryan Johnson, a tech entrepreneur and biohacker, has committed $2 million a year to reverse his biological age.
By Aniket Chakraborty
Apr 11, 2025
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Image Credit | @bryan_johnson | X
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His methods, like plasma exchange and blood transfusions from his son, have made headlines, but some experiments have gone awry.
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Johnson’s five-year experiment with rapamycin, an immunosuppressant, has raised questions about its true effects on aging.
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Inspired by a study suggesting rapamycin could extend lifespans, Johnson began using the drug for rejuvenation benefits.
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However, instead of reversing aging, Johnson noticed negative effects like mouth ulcers, slow-healing wounds, and high cholesterol.
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The most alarming issue was an increased resting heart rate, signaling potential health risks.
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A recent Yale study contradicted Johnson’s findings, revealing rapamycin could accelerate biological aging across 16 markers.
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Faced with this new data, Johnson stopped taking rapamycin and reassessed his approach to biohacking.
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Despite the setback, Johnson remains committed to his biohacking journey, emphasizing transparency about both successes and failures.
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Image Credit | @bryan_johnson | X
His self-funded experiment is a public quest to explore the limits of longevity, and while some see him as a visionary, others remain skeptical.
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Image Credit | @bryan_johnson | X