Scientists at Johns Hopkins have made a major HIV breakthrough using gene therapy.

By Aniket Chakraborty June 27, 2025 Arrow HEALTH & WELLNESS

The key lies in a molecule called an “antisense transcript” found within HIV itself.

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By enhancing this molecule, researchers can push the virus into deep dormancy.

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This dormant state, called viral latency, stops HIV from replicating inside the body.

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“We’re learning how to put HIV to sleep permanently,” said Dr. Fabio Romerio.

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Unlike daily antiretrovirals, this approach could be a one-time treatment.

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39.9 million people live with HIV globally—many still face lifelong medication.

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If successful in humans, gene therapy may offer a functional cure.

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Preclinical tests are next, as scientists seek safe delivery methods.

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A new era in HIV treatment may be on the horizon—without daily pills.

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